LONDON: Researchers are development a
young drug that will treat heart disease and angina pectoris without exacerbating any
inherent respiratory problems.
The University of Nottingham
researchers have already developed a molecule that is much more efficient at
discriminating between the heart and lungs than current drugs, EurekaAlert
reported Friday.
Researchers will be carrying out further studies to
improve the molecule to ensure that it is able to target the heart cells more
efficaciously - leaving the lungs untouched.
Jill Baker from the
University's School of Biomedical Sciences, world Health Organization is ahead the research, said:
"Once developed, this molecule will causal agent much less wheezing and shortness of
breath and should be able to be minded safely to the hundreds of thousands of
patients with both heart and lung diseases".
Doctors are extremely
leery of prescribing beta-blockers for patients suffering from spunk disease and
chronic impeding pulmonary disease (COPD), which aggravate respiratory
symptoms. COPD causes the destruction of lung tissue and increased mucus
production.
More information
Sunday 7 September 2008
Thursday 28 August 2008
Separate Submission Of Standard Lymphadenectomy In 6 Packets Versus En Bloc Lymphadenectomy In Bladder Cancer
�UroToday.com - The practice of lymphadenectomy during radical cystectomy for muscle invasive bladder cancer is not standardized. There is a wide edition in the number of nodes retrieved. Recent studies suggest that both the number of nodes remote and the method of submission of lymph leaf node specimens affect the treatment outcome. Some recent written document have likewise indicated that the lymph node specimens separately retrieved and submitted for pathology have a greater number of nodes compared to en axis resection. In the present study, we sought to identify if there was a difference in the number of nodes retrieved between on an individual basis retrieved and submitted pathological specimens and specimens from en axis resection.
Guidelines for the treatment of muscle-invasive bladder cancer by the European Association of Urology recommend limited pelvic node dissection, consisting of removal of the tissue in the obturator fossa in patients undergoing surgery with a curative intent.
Several authors have famous an improved 5-year survival rate with extensive pelvic lymph node dissection in the patients with node-involved bladder crab. Some investigators have noted that the quality of radical cystectomy procedure is judged by number of nodes retrieved.
They establish that a minimum of 9 nodes was needed to be examined to accurately assess nodal involvement. They likewise found that survival improved in both patients with and without node engagement as the number of the removed nodes increased.
They too evaluated the impact of submitting nodes en bloc or as separate packages and suggested that submitting nodes as separate packages not only when is easier, but as well optimizes the evaluation and number of the lymph nodes retrieved. Some studies indicate that lymphadenectomy in combination with RC can cure a small fraction of node-positive patients
We evaluated data on 77 patients with radical cystectomy and either standard pelvic lymph leaf node dissection or en axis lymphadenectomy were reviewed. Nodal dissection specimens during standard lymphadenectomy were sent for pathology examination in 6 separate containers marked as external iliac, internal iliac, and obturator groups from both sides. en bloc dissection specimens were sent in 2 containers marked as the right and the left wing pelvic nodes. Clinical and pathological findings of these two groups were compared in footing of the number of dissected lymph nodes, numeral of nodes with metastasis, lymph node density, and clinical outcomes. There were 34 patients with standard lymph client dissection and 43 with en axis lymphadenectomy. The median numbers pool of nodes removed per patient were 15.5 (range, 4 to 48) and 7.0 (kitchen stove, 1 to 24) in those with standard and en axis lymphadenectomy, respectively (P en bloc resection. Obturator nodes were the most normally involved nodes in our study.
We found that the number of the nodes retrieved per specimen increases significantly if dissection and submission of the nodes is done in the anatomically defined areas rather than en bloc submission.
Written by M. Hammad Ather, FCPS (Urol.), as section of Beyond the Abstract on UroToday.com
UroToday - the only urogenital medicine website with original content written by global urology key ruling leaders actively engaged in clinical practice.
To access the latest urogenital medicine news releases from UroToday, go to:
www.urotoday.com
Copyright � 2008 - UroToday
More info
Guidelines for the treatment of muscle-invasive bladder cancer by the European Association of Urology recommend limited pelvic node dissection, consisting of removal of the tissue in the obturator fossa in patients undergoing surgery with a curative intent.
Several authors have famous an improved 5-year survival rate with extensive pelvic lymph node dissection in the patients with node-involved bladder crab. Some investigators have noted that the quality of radical cystectomy procedure is judged by number of nodes retrieved.
They establish that a minimum of 9 nodes was needed to be examined to accurately assess nodal involvement. They likewise found that survival improved in both patients with and without node engagement as the number of the removed nodes increased.
They too evaluated the impact of submitting nodes en bloc or as separate packages and suggested that submitting nodes as separate packages not only when is easier, but as well optimizes the evaluation and number of the lymph nodes retrieved. Some studies indicate that lymphadenectomy in combination with RC can cure a small fraction of node-positive patients
We evaluated data on 77 patients with radical cystectomy and either standard pelvic lymph leaf node dissection or en axis lymphadenectomy were reviewed. Nodal dissection specimens during standard lymphadenectomy were sent for pathology examination in 6 separate containers marked as external iliac, internal iliac, and obturator groups from both sides. en bloc dissection specimens were sent in 2 containers marked as the right and the left wing pelvic nodes. Clinical and pathological findings of these two groups were compared in footing of the number of dissected lymph nodes, numeral of nodes with metastasis, lymph node density, and clinical outcomes. There were 34 patients with standard lymph client dissection and 43 with en axis lymphadenectomy. The median numbers pool of nodes removed per patient were 15.5 (range, 4 to 48) and 7.0 (kitchen stove, 1 to 24) in those with standard and en axis lymphadenectomy, respectively (P en bloc resection. Obturator nodes were the most normally involved nodes in our study.
We found that the number of the nodes retrieved per specimen increases significantly if dissection and submission of the nodes is done in the anatomically defined areas rather than en bloc submission.
Written by M. Hammad Ather, FCPS (Urol.), as section of Beyond the Abstract on UroToday.com
UroToday - the only urogenital medicine website with original content written by global urology key ruling leaders actively engaged in clinical practice.
To access the latest urogenital medicine news releases from UroToday, go to:
www.urotoday.com
Copyright � 2008 - UroToday
More info
Friday 8 August 2008
Sadie Frost's Business Goes Bust
Sadie Frost's company has gone bust.
The company, Frost-French, owed one creditor alone a astounding �3.3m ($6.6m).
Financial results for 2007 showed that they made a �774,533 ($1.5m) loss on top of the inning of debts of �900,000 ($1.8m). In 2005 it lost �388,102 ($700kk).
The company -- whose renown fans include Kate, Helena Christensen, Leah Wood and Jerry Hall -- has now bygone into administration.
Now, together with business married person and close friend, Jemima French, she's set up a new firm, Frost-French London Retail, to try out and turn around their losses.
A source tells Britain's Daily Mirror newspaper, "Sadie and Jemima were both absolutely devastated when they realized the company was heading into administration.
"They've place their heart and soul into FrostFrench for the past nine years so neither were prepared to go depressed without a fight.
"As a result they have place up a new company to invest in the label - and to pay back some of the money they owe.
"Sadie is compulsive to pay back every penny - but there's absolutely no guarantee this will happen.
"The next few months are crucial."
Sadie and Jemima have now closed the late opened King's Road shop in London. Their trading website has also folded although this is apparently due to be relaunched early following week.
Earlier this month they were ordered to pay �5,000 ($10k) in compensation to a former employee world Health Organization accused them of racial discrimination. The company was taken to an employment judicature by Aba Yankah wHO claimed she was pillaged after just one daylight because of her race.
More info
Tuesday 1 July 2008
Kate Moss Avoids Pete Doherty At Glastonbury - Video
Kate Moss braved the rain and mud to make her yearly pilgrimage to Glastonbury at the weekend.
Incorporating wellies into her festival wardrobe and flanked by an entourage of bodyguards, the ageing supermodel took up her position backstage – along with pal Lily Allen - to support boyfriend Jamie Hince, as he performed with his band The Kills.
But whilst organisers reportedly went to great lengths to ensure that Kate and co didn't run into her ex-boyfriend and one-time Glasto escort Pete Doherty, it seems that the Babyshambles frontman was getting nostalgic about their lost love.
Check out his touching musical tribute to Kate - entitled Bohemian Love - below.
Incorporating wellies into her festival wardrobe and flanked by an entourage of bodyguards, the ageing supermodel took up her position backstage – along with pal Lily Allen - to support boyfriend Jamie Hince, as he performed with his band The Kills.
But whilst organisers reportedly went to great lengths to ensure that Kate and co didn't run into her ex-boyfriend and one-time Glasto escort Pete Doherty, it seems that the Babyshambles frontman was getting nostalgic about their lost love.
Check out his touching musical tribute to Kate - entitled Bohemian Love - below.
Thursday 19 June 2008
George Takei of `Star Trek' gets marriage license
WEST HOLLYWOOD, Calif. —
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"Star Trek" star George Takei is ready to "live long and prosper" with his partner of 21 years.
Takei will marry 54-year-old Brad Altman on September 14th in Los Angeles.
The 71-year-old actor, known for his role as Sulu on the "Star Trek" sci-fi TV series, was the first to pay $70 for a marriage license in West Hollywood early Tuesday. The marriage license is good for 90 days.
Takei was jubilant, saying "it's going to be the only day like this in our lives and it is the only day like this in the history of America."
He told reporters and a swelling crowd outside the West Hollywood city auditorium "may equality live long and prosper."
The California Supreme Court has legalized same-sex marriage.
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Thursday 12 June 2008
Gina Gershon - Gershon Slams Clinton Claims
LATEST: GINA GERSHON has dubbed allegations she had an affair with ex-President BILL CLINTON a "crazy outrageous lie".
The July (08) issue of Vanity Fair magazine features a report by journalist Todd S. Purdum, in which he alludes to Clinton's infidelity following his recovery from heart surgery in 2004.
The article goes on to insinuate that Clinton made frequent stopovers in California to "visit" Gershon.
Gershon, who turns 46 on Tuesday (10Jun08), claims she has only met Clinton three times, and any suggestion they had a relationship is untrue.
Speaking on U.S. TV show Live with Regis and Kelly on Monday (9Jun08), She said, "That was kind of crazy. It was my day off, and I read this thing.
"It is such a crazy, outrageous lie. It has nothing to do with me and the end of the day
"I met him three times at events.
"It disturbed me on so many levels. I felt I had to stand up and say the truth."
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Friday 6 June 2008
Slaughter
Artist: Slaughter
Genre(s):
Rock: Hard-Rock
Metal: Heavy
Discography:
Back To Reality
Year: 1999
Tracks: 12
Revolution
Year: 1997
Tracks: 13
Fear No Evil
Year: 1995
Tracks: 12
The Wild Life (Remastered)
Year: 1992
Tracks: 16
The Wild Life
Year: 1992
Tracks: 3
Stick It To Ya
Year: 1990
Tracks: 15
Stick It Live
Year: 1990
Tracks: 5
Former Vinnie Vincent Invasion members Mark Slaughter and bassist Dana Strum formed Slaughter with guitar player Tim Kelly and drummer Blas Elias in 1988 in an attempt to cross over to pop out audiences. Their metal style's main focus is on catchy melodies and Mark Slaughter's telling vocal range, particularly his more or less nasal bone falsetto. Their first deuce studio albums sold rather well until their style fell out of favor with the alternative explosion. The group struggled passim the 1990s, and on February 5, 1998, Kelly died in an car fortuity; his last recordings appeared a class later on Aeonian Live. Still, the isthmus managed to regroup without him, releasing Back to Reality in 1999 with new guitarist Jeff Blando.
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